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Fix 'Windows Defender File Locked Cannot Access' Error - How to Resolve Cloudflare 521 Origin Unreachable-Windows 11: Outlook Won't Start Automatically

Updated 2026-06-18 09:34:27developer-tools
Fix 'Windows Defender File Locked Cannot Access' Error - How to Resolve Cloudflare 521 Origin Unreachable-Windows 11: Outlook Won't Start Automatically
Before changing system settings, save your work and note the exact error text so you can compare results after each step.

Extra verification checklist

  • Restart the affected app after changing permissions or configuration files.
  • Test the same workflow in a clean browser profile or a temporary user account.
  • Compare the result on another network if the error may be connection related.

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